Brain, Depression, Epigenetics: New Data
نویسندگان
چکیده
منابع مشابه
Epigenetics and depression: current challenges and new therapeutic options.
PURPOSE OF REVIEW Epigenetics comprises heritable but concurrent variable modifications of genomic DNA defining gene expression. The aim of this publication is to review the field of epigenetics in depression. Within this scope, we outline potential therapeutic options evolving in this young field of psychiatric research. RECENT FINDINGS Recently published papers show that epigenetic mechanis...
متن کاملEpigenetics and depression: return of the repressed.
INTRODUCTION Epigenetics has recently emerged as a potential mechanism by which adverse environmental stimuli can result in persistent changes in gene expression. Epigenetic mechanisms function alongside the DNA sequence to modulate gene expression and ultimately influence protein production. The current review provides an introduction and overview of epigenetics with a particular focus on prec...
متن کاملEpigenetics, brain evolution and behaviour.
Molecular modifications to the structure of histone proteins and DNA (chromatin) play a significant role in regulating the transcription of genes without altering their nucleotide sequence. Certain epigenetic modifications to DNA are heritable in the form of genomic imprinting, whereby subsets of genes are silenced according to parent-of-origin. This form of gene regulation is primarily under m...
متن کاملCancer Epigenetics: New Therapies and New Challenges
Cancer is nowadays considered to be both a genetic and an epigenetic disease. The most well studied epigenetic modification in humans is DNA methylation; however it becomes increasingly acknowledged that DNA methylation does not work alone, but rather is linked to other modifications, such as histone modifications. Epigenetic abnormalities are reversible and as a result novel therapies that wor...
متن کاملEpigenetics, brain, behavior, and the environment.
Early experiences can modify regulatory factors affecting gene expression in such a way that, although the DNA sequence itself is not changed, the individual's physiology and behavior is substantially influenced. In some instances these epigenetic effects are exerted upon exposure, while in other instances they are transmitted across generations via incorporation into the germline. Examples of ...
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ژورنال
عنوان ژورنال: Bulletin of Science and Practice
سال: 2020
ISSN: 2414-2948
DOI: 10.33619/2414-2948/54/21